Sterile solution 5 mgml and 10 mgml ropivacaine hydrochloride sodium chloride, water for injection, sodium hydroxide andor hydrochloric acid to adjust ph. Sweden oel twas 1 mgm3 france oel twa switzerland oel twas 2 mgm3 2 mgm3 version. Accidental release measures contain spill and collect, as appropriate. This document has been prepared in accordance with standards for workplace safety, which requires the inclusion of all known hazards of the product or its ingredients regardless of the potential risk. Ropivacaine hydrochloride hydrate safety data sheet section. Capitals indicate lifethreatening, underlines indicate most frequent. Material safety data sheet of ropivacaine hydrochloride. Ropivacaine hydrochloride is commonly marketed by astrazeneca under the trade name naropin. Ropivacaine is classified as fda pregnancy risk category b.
Find patient medical information for ropivacaine pf in 0. Ropivacaine has been used for up to 24 hours in clinical trials 01 02. Show this safety data sheet to the doctor in attendance. The ama owns the on the cpt codes and descriptions. Ropivacaine hydrochloride is the hydrochloride salt of ropivacaine, a local anesthetic of the amide type with analgesic activity. Ropivacaine injection fda prescribing information, side. Ropivacaine kabi information for health professionals. Injection contains ropivacaine hcl, which is a member of the amino amide.
Parenteral dosage forms ropivacaine hydrochloride injection. Ropivacaine hydrochloride posting date targeted official. Dec 01, 2019 ropivacaine hydrochloride injection, usp contains ropivacaine hcl which is a member of the amino amide class of local anesthetics. Apexbio ropivacaine hcl javascript seems to be disabled in your browser.
All information provided in support of this product, including sds and any product information leaflets have been developed and issued under the authority of the issuing pharmacopoeia. Cpt codes and descriptions are not public property and must always be used in compliance with law. Indications and clinical use adults 18 years of age. Your new online msds binder is a place for you to store the material safety data sheets.
The solution for injection is packed in 10 or 20 ml transparent polypropylene ampoules in blistered sterile containers. Chemical product and company information manufacturer name hospira, inc. Tecoland supplies ropivacaine hcl bulk active pharmaceutical ingredient api to the pharmaceutical industry. Material safety data sheet of ropivacaine hydrochloride contains identification of substance and details of the supplier of the safety data sheet. Ropivacaine hydrochloride monohydrate, 2sn2,6dimethylphenyl1propyl2piperidinecarboxamide hydrochloride monohydrate, sn2,6dimethylphenyl1propylpiperidine2carboxamide hydrochloride monohydrate, naropin hydrochloride monohydrate. Disclaimer the sds samples above are collected from the internet by chemblink and displayed here for the tutorial purpose only.
Naropin ropivacaine hcl injection a fresenius kabi site. Ropivacaine mesylate exerts neurotoxicity via upregulation of fas. Safety data sheet product name marcaine bupivacaine. Find patient medical information for ropivacaine hcl bulk on webmd including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Jan 24, 2020 ropivacaine hcl is a member of the amino amide class of local anesthetics. Ropivacine hydrochloride sodium chloride usp hydrochloric acid nf sodium hydroxide water for injection cas number 2112357 7647145 7647010 10732 7732185 additional information. Naropin ropivacaine hcl side effects, images, uses, dosage. Ropivacaine hcl mylan 2 mgml, solution for infusion ropivacaine. Australian product information ropivacaine kabi ropivacaine hydrochloride page 1 of 24 1 name of the medicine ropivacaine hydrochloride 2 qualitative and quantitative composition 3 pharmaceutical form ropivacaine kabi solution for injection is a sterile, isotonic, isobaric, aqueous solution of ropivacaine hydrochloride. Ropivacaine hydrochloride united states pharmacopeia usp reference standard. Ropivacaine hcl is a member of the amino amide class of local anesthetics.
Extreme high moderate low section 1 chemical product and company identification product name ropivacaine hydrochloride. Ropivacaine hydrochloride cas 2112357 msds download. Ropivacaine hcl api manufacturers suppliers drug master. Ropivacaine hydrochloride 2112357 not listed acute 4. Solution for infusion ropivacaine hcl mylan 2 mgml, solution for infusion contains as active substance 1. Uranium phosphide reacts with hydrochloric acid to release spontaneously flammable phosphines. Ropivacaine hydrochloride solution for injection msds. Ropivacaine hydrochloride united states pharmacopeia usp. Ropivacaine hydrochloride monohydrate sc208314 hazard alert code key. Identification of the substancemixture and of the companyundertaking product identifier naropin solution details of the supplier of the safety data sheet po box 1. Ropivacaine hydrochloride injection for epidural infusion. And address 275 north field drive lake forest, illinois 60045 usa note. Ropivacaine hydrochloride cas 2112357 msds guidechem. Welcome to contact us for further details including current dmf status for the product and up to date regulatory status of the manufacturing facility.
Assay dissolve an accurately weighed quantity of ropivacaine hydrochloride, approximately mg, in 10 ml of water and 40 ml of alcohol. Ropivacaine is used as a local in only one area anesthesia for a spinal block. Ropivacaine hydrochloride injection, usp is a sterile, isotonic solution that contains the enantiomerically pure drug substance, sodium chloride for isotonicity and water for injection. Naropin injection is a sterile, isotonic solution that contains the enantiomerically pure drug substance, sodium chloride for isotonicity and water for injection. Naropin ropivacaine hydrochloride injection, solution. A cumulative dose of 770 mg in 24 hours for postoperative pain management is well tolerated by most adults 01 02.
Ropivacaine hcl mylan 2 mgml, solution for infusion. Ropivacaine side effects, dosage, interactions drugs. Rubidium acetylene carbides burns with slightly warm hydrochloric acid. Ropivacaine hydrochloride injection, usp 10 is a sterile, isotonic solution that contains the enantiomerically pure drug substance. The name ropivacaine refers to both the racemate and the marketed senantiomer. Using naropin beyond recommended doses to increase motor block or duration of sensory block may negate its favorable cardiovascular advantages, in the event that an. J2795 hcpcs code ropivacaine hcl injection hcpcs registry. Ropivacaine binds to voltagegated sodium ion channels in the neuronal membrane, thereby preventing the permeability of sodium ions and resulting in a stabilization of the neuronal membrane and inhibition of depolarization. This material safety data sheet does not constitute the guaranty or specifications of the product.
Hydrochloric acid ropivacaine hydrochloride injection. An efficient and practical synthesis of ropivacaine. Our ropivacaine hcl is manufactured by cgmp compliant facility. Apexbio ropivacaine hcl javascript seems to be disabled in your. Ropivacaine hydrochloride type of posting notice of intent to revise posting date 31jan2020 targeted official date to be determined, revision bulletin expert committee chemical. Extreme high moderate low section 1 chemical product and company identification product name ropivacaine hydrochloride monohydrate statement of hazardous nature considered a hazardous substance according to osha 29 cfr 1910. Naropin may be associated with adverse reactions which are characteristic of those associated with other amidetype local anesthetics. Bupivacaine hydrochloride injection usp auromedics pharma llc. Learn about drug imprint, side effects, uses treating, dosage, interaction, overdose, and warnings. Store at 20 to 25c 68 to 77f see usp controlled room temperature. What ropivacaine looks like and contents of the pack ropivacaine solution for injection is a clear, colourless, sterile, isotonic, isobaric aqueous solution for injection. Chemical product and company identification manufacturer name and address.
General description this product is provided as delivered and specified by the issuing pharmacopoeia. Dailymed ropivacaine hydrochloride injection, solution. Nov 09, 2018 ropivacaine is an anesthetic numbing medicine that blocks the nerve impulses that send pain signals to your brain. Ropivacaine hcl is an anaesthetic agent and blocks impulse conduction in nerve fibres through inhibiting sodium ion influx reversibly. Ropivacaine binds to voltagegated sodium ion channels in the neuronal. Ropivacaine hydrochloride injection, usp, compare to naropin. Jan 03, 2018 naropin injection contains ropivacaine hcl which is a member of the amino amide class of local anesthetics. Quantitative mass spectrometric analysis of ropivacaine. Sds of ropivacaine hydrochloride, safety data sheets, cas. Ropivacaine hydrochloride was developed as the pure sisomer and has an enantiomeric purity of 99%.
Dailymed naropin ropivacaine hydrochloride injection, solution. The pka of ropivacaine is approximately the same as bupivacaine 8. Each ml of 1 n sodium hydroxide is equivalent to 310. Calcium carbide reacts with hydrogen chloride gas with incandescence.
Identification of the substancemixture and of the companyundertaking. Ropivacaine hcl mylan 2 mgml, solution for injection contains as active substance 1. Ropivacaine hydrochloride injection, usp fresenius kabi canada. Material safety data sheet ropivacaine hydrochloride monohydrate sc208314 hazard alert code key.
It is present as a racemic mixture of the enantiomers containing equal proportions of the s and r forms. Marcaine bupivacaine hydrochloride with epinephrine injection 1. Wellcontrolled studies have not been performed in pregnant women. The ph of a saturated solution of ropivacaine hydrochloride. Safety data sheet according to federal register vol. Ropivacaine hydrochloride drug information, professional. Section 5 fire fighting measures general information. Details of the supplier of the safety data sheet 2. Ropivacaine monohydrochloride cas 98717158 msds guidechem. As in any fire, wear a selfcontained breathing apparatus in pressuredemand, mshaniosh approved or equivalent, and full protective. Naropin injection is a sterile, isotonic solution that contains the.
Naropin medical information naropin ropivacaine hcl. Our products are available from authorized distributors. Hospira, formerly the hospital products division of abbott laboratories, was. Ropivacaine is an aminoamide local anaesthetic drug commonly marketed by astrazeneca under the trade name naropin. Naropin ropivacaine hydrochloride dose, indications. For complete ordering information, please contact your local pharmaceutical distributor.
636 1436 800 171 816 466 786 345 98 1172 1276 64 684 204 1040 1489 1522 1422 758 1404 3 163 492 1417 17 873 82 1103 555 539 896 42 749 7 220 1454